GHRP-2 5mg/10mg
GHRP-2 – hexapeptide ghrelin receptor agonist, studied in relation to growth hormone and IGF-1 release. Price and batch analysis.
29.00 EUR · In stock
This product is intended solely for scientific and research use and is not an approved medicinal product. It is not intended for the diagnosis, treatment or prevention of disease in humans or animals. It has not been approved by the FDA, the EMA or any national regulator. The information on this page is provided for scientific information purposes only and does not constitute medical advice, a recommendation for use, or any claim of clinical efficacy or safety.
GHRP-2 – What the Peptide Is
GHRP-2 is a synthetic hexapeptide belonging to the family of growth hormone-releasing peptides. It acts on the ghrelin receptor and is among the most thoroughly studied members of the group.
The compound was described before the discovery of ghrelin itself, meaning the receptor was identified through artificial ligands before its natural partner was found. This fact is often noted in historical reviews of the field.
Compared to GHRP-6, GHRP-2 is described as having a less pronounced effect on appetite while showing comparable secretagogue activity.
Mechanism of Action
The molecule binds to the ghrelin receptor in the pituitary gland and the hypothalamus. Pituitary binding leads to growth hormone release via a pathway independent of the GHRH receptor.
The two mechanisms – GHRH and ghrelin – act jointly, which is the basis for research on their combined activation. The response to simultaneous stimulation is described as greater than the sum of the individual effects.
Hypothalamic binding is involved in appetite regulation, with this component being less pronounced in GHRP-2 than in GHRP-6.
Research Data and Observations
Observations track growth hormone and IGF-1 concentrations, as well as effects on cortisol and prolactin. A certain increase in both is reported, distinguishing the compound from selective analogs.
A separate line of research examines the diagnostic application of the compound in assessing pituitary reserve.
A reduction in response is reported with prolonged administration, attributed to decreased receptor sensitivity.
When interpreting the published data, the distinction between preclinical and clinical conditions should be taken into account. Results from cell cultures and animal models describe a mechanism but do not allow quantitative conclusions for human conditions.
Dose ranges used in preclinical studies are often not directly translatable due to differences in metabolism between species. This limitation is consistently noted in review papers.
Example Calculations
The calculations below are purely mathematical examples showing the relationship between total substance amount, solvent volume, and resulting concentration. They do not constitute a dosing recommendation, administration schedule, or instructions for use.
When reconstituting 5 mg with 2 ml of bacteriostatic water:
The resulting concentration is 2.5 mg/ml, with 0.40 ml containing 1 mg of substance.
Example values:
- 0.1 ml = 0.25 mg
- 0.2 ml = 0.5 mg
- 0.3 ml = 0.75 mg
- 0.4 ml = 1 mg
- 0.5 ml = 1.25 mg
When reconstituting 10 mg with 2 ml of bacteriostatic water:
The resulting concentration is 5 mg/ml, with 0.20 ml containing 1 mg of substance.
Example values:
- 0.1 ml = 0.5 mg
- 0.2 ml = 1 mg
- 0.3 ml = 1.5 mg
- 0.4 ml = 2 mg
- 0.5 ml = 2.5 mg
Overview of Scientific Publications
The literature on GHRP compounds has accumulated over three decades and includes both mechanistic studies and diagnostic applications.
Comparison between individual representatives requires attention due to differences in selectivity and the ranges studied.
Safety data from studies
Reported observations include increases in cortisol and prolactin, injection site reactions, and a short-lived sensation of hunger.
A concentration-dependent effect and a decrease in response with prolonged administration are reported.
A general limitation for compounds in this category is the absence of long-term controlled studies in humans. The available information describes mechanism and short-term observations, not a safety profile for prolonged use.
This product is intended exclusively for research purposes. It is not a food, dietary supplement, or medicinal product and is not intended for the diagnosis, treatment, or prevention of any disease.