A library of published PurePeptide materials about peptides, their properties and research context. The topics below bring together available articles with short excerpts and links to the full text.
When evaluating scientific information, distinguish laboratory, preclinical and clinical findings. The model, methods, limitations and publication date all matter. A single finding is not sufficient for a general conclusion, and results obtained under different experimental conditions are not necessarily comparable.
These materials are for information and research purposes. They are not medical advice and do not establish safety or efficacy for use in humans.
Sources: Falutz J. et al., The New England Journal of Medicine, 2007; FDA Prescribing Information for EGRIFTA; Fourman L.T. et al., JCI Insight, 2020; Russo S.C. et al., 2024. Introduction Tesamorelin is a synthetic analog
Source: Lee C. et al., Cell Metabolism, 2015, 10.1016/j.cmet.2015.02.009 Research objective To evaluate whether the mitochondrial peptide MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) can regulate glucose
Retatrutide is a triple agonist of GIP, GLP-1 and glucagon receptors. In a 48-week clinical trial in obese adults, it showed weight reduction of up to 24.2%.
GHK-Cu is a small tripeptide that shows impressive regenerative, anti-inflammatory, and antioxidant properties on skin and nerves. Applications in medicine.
CJC-1295 – a long-acting GHRH analog – stimulates the GH/IGF-1 axis, leading to a sustained increase in growth hormone and IGF-1 levels.
BPC-157 is a peptide with demonstrated safety and good tissue penetration. Studies show a short half-life and potential for the recovery of muscles, tendons, and organs.
Weekly administration of semaglutide 2.4 mg leads to a 14.9% average weight loss over 68 weeks and improvements in metabolic and cardiovascular parameters.
Tirzepatide shows up to 21% weight reduction over 72 weeks and improves metabolic markers in people with overweight and obesity.
TB-500 (Thymosin Beta-4) stimulates regeneration, angiogenesis, and reduces inflammation. Suitable for muscle and tendon injuries, with an excellent safety profile.
IGF-1 LR3 is a peptide with anabolic effects and prolonged action, stimulating muscle growth and cellular regeneration through activation of IGF-1R signaling.
hGH Frag 176-191 shows a lipolytic effect, reduces weight gain and stimulates fat oxidation in obesity models.
Sermorelin stimulates the natural secretion of growth hormone, mimics physiological pulsatility, and offers a safer alternative to rhGH in adults.
Hexarelin – a synthetic hexapeptide of the GHRP class – stimulates growth hormone (GH) release in a dose-dependent and reproducible manner.
Ipamorelin is the first selective GHRP-receptor agonist that stimulates the release of growth hormone (GH) without significant effect on ACTH or cortisol.
A clinical study shows that GHRP-2 increases appetite and food intake by more than 35%, while also increasing growth hormone levels without side effects.