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Peptides Tested at Janoshik Labs
Sermorelin is a synthetic peptide composed of 29 amino acids. It is an analog of the endogenous hormone GHRH (Growth Hormone Releasing Hormone), which stimulates the pituitary gland to secrete its own growth hormone (GH).
Unlike the direct administration of recombinant GH, sermorelin supports the natural regulation of secretion, preserving the physiological feedback mechanisms.
Sermorelin is being studied for its possible effects on:
Stimulating growth hormone secretion – in research models, an increase in endogenous GH from the pituitary gland has been observed.
Muscle mass and strength – an effect on protein and collagen synthesis has been described.
Joint and bone health – an influence on bone mineralization has been observed.
Regeneration and recovery – under experimental conditions, a reduction in recovery time after exertion has been described.
Sleep quality – an observed effect on deep sleep phases.
In scientific literature, subcutaneous administration of 100-300 μg once daily is described, usually before sleep, to synchronize with physiological GH pulses.
For 5 mg + 3 ml bacteriostatic water: 1.67 mg/ml → 0.06 to 0.18 ml daily
For 10 mg + 3 ml bacteriostatic water: 3.3 mg/ml → 0.03 to 0.09 ml daily
Example values for 5 mg:
0.06 ml = 100μg
0.18 ml = 300 μg
0.15 ml = 250 μg
0.30 ml = 500μg
0.45 ml = 750μg
Example values for 10 mg:
0.03ml = 100μg
0.09ml = 300 μg
0.15 ml = 500 μg
0.30 ml = 1.0 mg
Sermorelin has been studied in clinical and preclinical settings.
In endocrinology, it has been used for the diagnosis of GH deficiency and as a therapeutic agent to stimulate endogenous growth hormone.
In gerontology and regenerative medicine, it is being investigated for its potential to improve body composition, muscle tone, and bone density.
In sports medicine, there is interest in its effects on recovery and adaptation after exertion.
Sermorelin is prohibited by WADA for use in professional sports, as it may:
- stimulate growth hormone secretion
- improve tissue recovery
- increase muscle mass and strength
- aid in fat reduction
In preclinical conditions, adverse reactions are usually rare and mild, including:
- redness or pain at the injection site
- headache
- dizziness
- mild fluid retention
Less commonly observed are insomnia or palpitations.
The information has been collected and systematized from various scientific sources and studies. It serves educational purposes only and should not be used for the diagnosis, treatment, or prevention of diseases.