What is CJC-1295?
CJC-1295 (Mod GRF 1-29) is a synthetic analogue of Growth Hormone Releasing Hormone (GHRH) composed of 29 amino acids. The modified version (Mod GRF 1-29) contains substitutions of several amino acids that make it more stable and biologically active compared to the original Sermorelin. Published data have shown that CJC-1295 stimulates the pituitary gland to secrete growth hormone (GH) by a natural physiological mechanism, enhancing physiological GH pulses. It is often combined with GHRP peptides (e.g. Ipamorelin) for a synergistic effect on GH secretion.
Observations on CJC-1295
CJC-1295 (Mod GRF 1-29) is being studied for its possible effects on:
Growth hormone stimulation - observed activation of GH pulses and IGF-1 secretion.
Effect on anabolism and protein synthesis.
Joint and bone health - observed effect on mineralization and regeneration of bones and tendons.
Regeneration and recovery - observed effect on recovery processes after exercise.
Sleep quality regulation - supports deep sleep phases.
Anti-aging effects - observed effect on tissue regeneration and catabolic processes.
Metabolic effect - An effect on lipolysis has been observed in research models.
Scientific data
CJC-1295 has been studied in clinical and preclinical settings.
In endocrinology, it shows effective increases in GH and IGF-1 with good tolerability.
It is being studied in sports medicine for its role in recovery, muscle growth, and fat reduction.
In gerontology, interest is related to its potential to slow down aging processes by maintaining high levels of GH and IGF-1 in old age.
Its combination with GHRP peptides has been reported to be more effective than its use alone.
Dosage and administration
The scientific literature describes subcutaneous administration once daily at 100-300 μg daily, usually in the evening before bedtime.
At 5 mg + 3 ml bacteriostatic water:
Concentration = 1.67 mg/ml → 0.06 ml = 100 μg
Example values for 5 mg:
0.06 ml = 100 μg
0.12 ml = 200 μg
0.18 ml = 300 μg
0.24 ml = 400 μg
Application in sports
CJC-1295 is banned by WADA for use in professional sports because it can:
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stimulates the secretion of growth hormone
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accelerate muscle and tendon recovery
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increase muscle mass and strength
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help reduce fat
Possible side effects
Reported side effects are rare and usually mild:
Less commonly, dizziness or temporary changes in appetite may occur.
The information has been collected and systematized from various scientific sources and studies. It serves educational purposes only and should not be used for the diagnosis, treatment or prevention of diseases .